Maximum plasma concentration is reached after 4-12 hours after injection. The half-life of 29-30 hours and therefore, in the case of daily intramuscular injection, there may be drug accumulation. Gonadotropin androgel side effects excreted by the kidneys. 10-20% of the dose is found in urine in an unmodified form, while the main part is excreted as fragments of β-chain.
Indications hypogonadal (due to a violation of the hypothalamus activity and pituitary gland). In women: – induction of ovulation in infertility, caused anovulation or impaired follicular maturation; – Preparation of follicles for puncture in controlled ovarian hyperstimulation programs (for assisted reproductive technologies); – maintenance gnc testosterone. phase corpus luteum In boys and men: – hypogonadotropic hypogonadism; – delayed puberty, due to the lack of gonadotrophic pituitary function; – cryptorchidism not due to anatomical obstruction.
Contraindications: General: organic androgel side effects lesions, such as tumors of the pituitary gland, the hypothalamus; gonadal dysgenesis; Hypersensitivity to the or to any component of the drug;hypothyroidism; adrenal insufficiency; hyperprolactinemia; . deep vein thrombosis in women: hormone-dependent tumor or currently suspected them (uterine cancer, breast cancer); Ovarian hyperstimulation syndrome in history; primary ovarian failure, bleeding or spotting from the vagina (not associated with menstruation) of unknown etiology; malformations of reproductive organs in which pregnancy is not possible; fibroid tumors of the uterus, in which offensive and child bearing impossible; Infertility is not associated with ovulation (eg, cervical or tubal origin); early menopause; obstruction of the fallopian tubes trenbolone side effects; normal pregnancy and lactation. In men: androgen tumors (prostate cancer, breast cancer, testicular tumor); Infertility is not associated with hypogonadotropic hypogonadism; . Severe renal insufficiency Boys: children up to 3 years; precocious puberty. If you have one of these diseases, before taking this medication, you should consult with your doctor.
Precautions Androgel side effectsis used in patients with coronary artery disease, congestive heart failure; epilepsy, migraine (including history); bronchial asthma, chronic renal failure, hypertension; in women with risk factors for thrombosis (thrombosis or thromboembolism, or relatives of the 1st degree relatives, obesity , thrombophilia); boys in the prepubertal period.
Dosing and Administration Drug treatment should be done only under medical supervision, having the appropriate specialization and experience in the treatment of infertility. The solution for injection should be prepared androgel side effects immediately before administration using the supplied solvent. Do not use if solution contained undissolved particles or it opaque. In women: to induce ovulation of follicles, and to puncture preparation administered . In order to maintain the corpus luteum of the ovary phase 3, 6 and 9 days after ovulation administered at 1500-5000 ME formulation.In boys and men: For the differential diagnosis of cryptorchidism and anorchia boys and to assess testicular function with hypogonadotropic hypogonadism once introduced . In hypogonadotropic hypogonadism is administered tren steroid time per week in combination with drugs menopausal gonadotropin . For the treatment of cryptorchidism boys 3-6 years administered 1 time per week androgel side effects product for 3 weeks (if necessary, in combination with a gonadotropin releasing hormone (GnRH)). For accelerating puberty in boys introduced times per week for 3 months.
Overdose In connection with the use of high in women with ovulation induction may develop severe syndrome. Symptoms: a sharp pain in the abdomen (especially in the groin area), nausea, vomiting, diarrhea, flatulence, oliguria, tachypnea, swelling lower limbs, in severe cases – hypovolemia, blood clots, disruption of water and electrolyte balance, ascites, peritonitis, hydrothorax, acute pulmonary insufficiency, thromboembolic complications. This condition is accompanied by the development of large ovarian cysts with danger of rupture and intra-abdominal bleeding, ascites, hydrothorax and the risk of thromboembolic complications.